Lowering the risk threshold for statin treatment has a small numerical impact on the whole population. A high proportion has risk levels that merits primary CHD prevention. For end-users of diabetes models that include UKPDS 82 risk equations, an important question is how well these new equations perform. Reducing the CHD risk threshold from 30 to 15% for statin initiation will identify an additional 0.5% of the total population for this treatment.Ĭonclusions Both methods are comparable in identifying at-risk patients under NICE recommendations. At a risk threshold of 30%, the UKPDS risk engine identified more patients for statin. Both methods identified approximately 65% of patients to be eligible for aspirin and statin if NICE recommendations were followed. Results UKPDS risk engine calculated significantly higher mean 10-year CHD risk (UKPDS vs. The Oxford Centre for Diabetes, Endocrinology and Metabolism, UKPDS Risk Engine. The proportion of additional patients identified for statin in the Scarborough population as a consequence of CHD risk threshold reduction from 30 to 15% (as recommended by NICE) was also determined. 2.0) was downloaded from the website and used to analyze the data ( 2020. The presence of traditional and nontraditional risk factors that frequently coexist with type 2 diabetes. Abstract: Individuals with type 2 diabetes have a two to four fold increased risk for developing cardiovascular disease than persons without diabetes. The differences in the proportion of patients identified for aspirin and statin under JBS and National Institute for Clinical Excellence (NICE) guidelines by these two methods were determined. Keywords: Cardiovascular risk, Diabetes mellitus, UKPDS risk engine, Diabetes PHD, DECODE. Their absolute 10-year CHD risks were calculated. ![]() Methods Seven hundred Type 2 DM patients without arterial complications were identified from nine general practices in the Scarborough area. The United Kingdom prospective diabetes study is a multicentre, prospective, randomised, intervention trial, started in 1977, which aims primarily to determine whether improved glycaemic control in noninsulin dependent diabetic patients will prevent diabetic complications and their associated morbidity and mortality.6 The secondary aim is to. Aims To assess differences between absolute coronary heart disease (CHD) risks calculated by Joint British Societies (JBS) risk calculator and UKPDS risk engine and its impact on CHD primary prevention management in diabetes mellitus (DM).
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